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LAB PUBLICATIONS
Arold, S.P., N. Malavia, and S.C. George. Mechanical compression attenuates normal human bronchial epithelial wound healing . Resp. Res., (in final review), 2009.
Jiang, J., N. Malavia,
V. Suresh, and S.C. George. Nitric oxide gas phase release in human small airway epithelial cells. Resp. Res., (in final review), 2009.
Griffith, C.K. and S.C. George. The effect of hypoxia on in vitro prevascularization of a thick soft tissue. Tiss. Engr. (in final review), 2009.
Malavia,
N, C.B. Raub, S.B. Mahon, M. Brenner, R.A. Panettieri, and S.C. George. Airway epithelium stimulates smooth muscle proliferation. Am. J. Resp. Cell Molec. Biol., (in final review), 2009.
Chen, X., A.S. Aledia, C.M. Ghajar,
C.K. Griffith, A.J. Putnam, C.C.W. Hughes,
and S.C. George. Prevascularization of a fibrin-based tissue construct accelerates the formation of functional anastomosis with host vasculature.
Tiss. Eng., (in press), 2008.
Puckett, J.L.
and S.C. George. Patitioning exhaled nitric oxide to non-invasively assess asthma.
Resp. Physiol. Neurobiol., 163:166-177, 2008.
George,
S.C. How accurately should we estimate the anatomical source of exhaled
nitric oxide? (editorial) J. Appl. Physiol., 104:909-991, 2008.
Suresh,
V.*, D.A. Shelley*, H.-W. Shin, and S.C.
George. Effect of heterogeneous ventilation and nitric oxide production
on exhaled nitric oxide profiles. J. Appl. Physiol., 104:1743-1752, 2008. *contributed
equally as 1st authors to this manuscript.
Malavia,
N, J.D. Mih, C.B. Raub, B.T. Dinh, and S.C. George. IL-13 induces a bronchial
epithelial phenotype that is profibrotic. Resp. Res., 9:27, 2008.
Raub,
C.B., J. Unruh, V. Suresh, T. Krasieva, T. Lindmo, E. Gratton,
B.J. Tromberg, and S.C. George. Image correlation spectroscopy of multiphoton
images correlates with collagen mechanical properties. Biophys. J., 94:2361-2373,
2008.
Ghajar,
C.M., X. Chen, J.W. Harris, V. Suresh, C.C.W. Hughes, N.L. Jeon, A.J. Putnam,
and S.C. George. The effect of matrix density on 3-D capillary morphogenesis.
Biophys. J., 94:1930-1941, 2008.
Shelley,
D.A.*, H.-W. Shin*, and S.C. George. In silico modeling of nitric oxide
production, transport, and consumption. Drug Disc Today: Dis. Mod.., 4(3):147-53,
2007. *contributed equally as 1st authors
to this manuscript.
Suresh,
V., J.D. Mih, and S.C. George. Measurement of IL-13-induced iNOS-derived
gas phase nitric oxide in human bronchial epithelial cells. Am. J. Resp.
Cell Molec. Biol., 37:97-104, 2007.
Ghajar,
C.M., V. Suresh, S.R. Peyton, C.B. Raub, S.C. George, and A.J. Putnam.
A Novel 3-D Model to Quantify Metastatic Melanoma Invasion. Molec. Cancer
Ther., 6(2):552-561, 2007.
Raub,
C.B, V. Suresh, T. Krasieva, J. Lyubovitsky, J.D. Mih, A.J. Putnam,
B.J. Tromberg, and S.C. George. Noninvasive assessment of collagen gel
microstructure and mechanics using multiphoton microscopy. Biophys.
J., 92:2212-2222, 2007.
Shin,
H-W., D.A. Shelley, A. Fitzpatrick, B. Gaston, and S.C. George. Airway
nitric oxide is reduced following phosphate buffered saline inhalation
in asthma. J. Appl. Physiol., 102:1028-1032, 2007.
Condorelli,
P., H-W Shin, A.S. Aledia, P.E. Silkoff, and S.C. George. A simple
technique to characterize proximal and peripheral nitric oxide
exchange using constant flow exhalations and an axial diffusion
model. J. Appl. Physiol., 102:417-425, 2007.
Thompson,
H.G.R., D.T. Truong, C. Griffith, and S.C. George. A three-dimensional
in vitro model of angiogenesis in the airway mucosa. Pulm. Pharm.
Therap., 20:141-148, 2007.
Thompson,
H.G.R., J.D. Mih, T.B. Krasieva, B.J. Tromberg, and S.C. George. Epithelial-derived
TGF-beta2 modulates basal and wound healing subepithelial matrix homeostasis.
Am. J. Physiol. - Lung Cell Molec Physiol., 291:1277-1285, 2006. Shin,
H-W., C.D. Schwindt, A.S. Aledia, C.M Rose-Gottron, J.K. Larson,
R.L. Newcomb, D.M. Cooper, and S.C. George. Exercise-induced bronchoconstriction
alters airway nitric oxide exchange in a pattern distinct from spirometry.
Am. J. Physiol. - Reg. Int. Comp., 291:1741-1748, 2006.
Ghajar,
C.M., K.S.
Blevins, C.C.W. Hughes, S.C. George, and A.J. Putnam. Mesenchymal Stem
cells enhance
angiogenesis in mechanically viable prevascularized
tissues via early MMP upregulation. Tiss. Engr., 12:2875-2888, 2006.
Shin,
H-W., P. Condorelli, and S.C. George. Examining axial diffusion of nitric
oxide in the lungs using heliox and breathhold. J. Appl. Physiol., 100:623-630,
2006.
Shin,
H-W., P. Condorelli, and S.C. George. A new and more accurate technique to
characterize airway nitric oxide using different breathhold times. J. Appl.
Physiol. 98:1869-1877, 2005.
Griffith, C.K., C. Miller,
R.C.A Sainson, J.W. Calvert, N.L. Jeon, C.C.W. Hughes, S.C. George. Diffusion
limits of an in vitro thick prevascularized tissue. Tiss. Engr. 11:257-266,
2005.
Shin,
H-W., P. Condorelli, C.M Rose-Gottron, D.M. Cooper, and S.C. George. Probing
the impact of axial diffusion on nitric oxide exchange using heliox.. J.
Appl. Physiol. 97:874-882, 2004.
Condorelli,
P., H-W. Shin, and S.C. George. Characterizing airway and alveolar nitric
oxide exchange during tidal breathing using a three-compartment model. J.
Appl. Physiol. 96:1832-1834, 2004.
George,
S.C., M. Hogman, S. Permutt, and P.E. Silkoff. Modeling pulmonary nitric
oxide exchange. J. Appl. Physiol. 96:831-839, 2004.
Shin,
H-W., C.M. Rose-Gottron, D.M. Cooper, R.L. Newcomb, and S.C. George. Airway
diffusing capacity of nitric oxide and steroid therapy in asthma. J. Appl.
Physiol., 96:65-75, 2004.
Jeh, H. and S.C. George. Encapsulation
of PROLI/NO in biodegradable microparticles. J. Microencap.. 21(1):3-13,
2004.
Shin,
H-W., C.M. Rose-Gottron, D.M. Cooper, M. Hill, and S.C. George. Impact of
high intensity exercise on flow-independent nitric oxide exchange parameters
in healthy adults. Med. Sci. Sport Exer.. 35:995-1003, 2003.
Agarwal, A., J. Mih, and S.C. George. Soluble and fixed protein expression
in an in vitro model of airway remodeling in asthma. Allergy Asthma Proceed.
24:35-42, 2003.
Shin, H-W.
and S.C. George. Impact of axial diffusion on nitric oxide exchange in the
lungs. J. Appl Physiol 93:2070-2080, 2002.
Condorelli,
P. and S.C. George. Free nitric oxide diffusion in the bronchial microcirculation.
Am. J.. Physiol. 283:H2660-H2670, 2002.
Jeh, H. and S.C. George. Dynamic
modeling of nitric oxide delivery to pulmonary arterioles. Ann. Biomed. Engr.
30:1-15, 2002.
Shin,
H-W., C. Rose-Gottron, R. Sufi, F. Perez, D. Cooper, A.F. Wilson, and S.C.
George. Flow-independent nitric oxide exchange parameters in cystic fibrosis.
Am. J. Resp. Crit. Care Med.. 165:349-357, 2002.
Shin,
H-W., C. Rose-Gottron, F. Perez, D. Cooper, A.F. Wilson, and S.C. George.
Flow-independent nitric oxide exchange parameters in healthy adults. J. Appl.
Physiol.. 91:2173-2181, 2001.
Kwon,
S. and S.C. George. Mechanisms of synergistic cytokine-induced nitric oxide
production in human alveolar epithelial cells. Nitric Oxide: Biol. Chem.
5(6):534-546, 2001.
Tsoukias,
N.M., H-W. Shin, A.F. Wilson, and S.C. George. A single breath technique
with variable flow rate to characterize NO exchange dynamics in the lungs.
J. Appl. Physiol.. 91:477-487, 2001.
Tsoukias,
N.M., and S.C. George. Impact of volume-dependent diffusing capacity on exhaled
nitric oxide concentration. Ann. Biomed. Engr. 29(9):731-739, 2001.
Condorelli,
P. and S.C. George. A kinetic analysis of soluble guanylate cyclase activation
by free nitric oxide. Biophys. J. 80:2110-2119, 2001.
Agarwal,
A., M. Coleno, W. Wu, C.H. Sun, B.J. Tromberg, and S.C. George. Two-photon
laser scanning microscopy of epithelial cell-modulated collagen density in
engineered human lung tissue. Tiss. Engr. 7(2):191-202, 2001.
Shin, H-W. and S.C.
George. Microscopic modeling of nitric oxide and S-nitrosoglutathione kinetics
and transport in human airways. J. Appl. Physiol. 90(3):777-788, 2001.
Högman, M, D. Lúdvíksdóttir,
S.D. Anderson, S.C. George, L. Håkansson, H.K. Chan, P. Meriläinen,
H. Hedenström. Inhaled mannitol shifts exhaled nitric oxide in opposite
directions in asthmatics and healthy subjects. Resp. Physiol. 124(2):141-150,
2001.
Tsoukias,
N.M. D. Dabdub, A.F. Wilson, and S.C. George. Effect of alveolar volume and
sequential filling on the diffusing capacity of the lung: II. experiment.
Resp. Physiol. 120(3):250-271, 2000.
Tsoukias,
N.M., A.F. Wilson, and S.C. George. Effect of alveolar volume and sequential
filling on the diffusing capacity of the lung: I. theory. Resp. Physiol.
120(3):231-249, 2000.
Kwon,
S. and S.C. George. Synergistic cytokine-induced nitric oxide production
in human alveolar epithelial cells. Nitric Oxide: Biol. Chem. 3(4):348-357,1999.
Condorelli,
P. and S.C. George. Theoretical determination of gas phase mass transfer
coefficients for endogenously produced gases in the human airways. Ann. Biomed.
Engr. 27(3):326-339, 1999.
Tsoukias, N.M.
and S.C. George. A two-compartment model of pulmonary nitric oxide exchange
dynamics. J. Appl. Physiol. 85(2):653-666, 1998.
Tsoukias, N.M.,
Z. Tannous, A.F. Wilson, and S.C. George. Single exhalation profiles of NO
And CO2 in humans: effect of dynamically changing flow rate. J. Appl. Physiol.
85(2):642-652, 1998.
Bui, T.D., D. Dabdub, and S.C. George. Modeling the bronchial circulation
with application to soluble gas exchange: description and sensitivity analysis.
J. Appl. Physiol. 84(6):2070-2088, 1998.
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